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Sunday brings the initial Wear-Tyne derby since 2024, but who will emerge victorious – the Black Cats or the Magpies?
"Throughout the majority of last season, you couldn't have imagined the Wearside club getting promoted and challenging with Eddie Howe's Newcastle, let alone being above them in the table," stated analyst Chris Sutton.
"Things are very different now, and the way they play convinces me they've got a real chance."
Sutton is making scoreline guesses for all 380 Premier League games this season, against AI, fans and a range of guests.
For week 16, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the national gaming squad – the Football Association's formal esports team – at the EA Sports FC Uefa eEuro 2025 finals tournament, which takes place at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, Instagram Live and short-form video channels, as well as EA Sports FC Twitch and its YouTube counterpart and England's Twitch.
Do you agree with their forecasts? Feel free to submit your own predictions below.
The most commonly selected scoreline selected for each game is featured in the scoreboards at the bottom of this page.
A correct result (choosing a win, draw or defeat) is worth ten points. A perfect prediction earns 40 points.
Ray, who represents his club side and the Premier League champions as well as England, is entering the fray at the eEuros finals after successfully navigating the qualification rounds.
A group of eight will play for their countries at the finals in a knockout format, playing for a six-figure prize fund and a highly sought-after spot in the global championship qualifiers, with the Danish representative Anders Vejrgang defending the title he won last year.
"I am feeling really good for it," Ray said. "I've got a really good coach with me and practice has been going well.
"It's always an honour to play for your country. Naturally when you are younger, you dream about doing it as an professional footballer, but when you enter this job and there is an opportunity to represent England, wearing the Three Lions is something special.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"I believe he is the top competitor in the world so defeating him in a tournament like this just delivers a massive injection of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were excellent against Arsenal at the end of November, when they got a draw after being reduced to 10 men, and it seemed here we go, they could possibly be challengers for the crown.
Since then, however, they were overpowered by Leeds, looked uninspired against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to restore momentum, but it is a tough ask because Everton are such a potent team.
Two of their stars are playing exceptionally and they have got a bit of momentum at the moment.
Current evidence suggests you would likely back the visitors, while the most prudent prediction would likely be a draw, but I'm throwing caution to the wind.
Chelsea haven't given me any good cause to back them recently, but I just have a gut instinct they will take this one because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be interesting to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the discussion with Mohamed Salah this week.
Slot shouldn't need to put up with that drama. I know Salah has been a legend for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their formation against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is selected for this game, but the only way he is going to be reintegrated is if he makes amends.
Slot's focus will be on winning this game, but it is a difficult fixture.
One might suggest it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are defensively susceptible too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their energy spent at the San Siro will have taken out of them.
I put a couple of Brighton players in my FPL team, so they will almost certainly blank - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
Sunderland have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Aside from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, especially straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their fatigue is likely to be a key element in how this game goes because of Sunderland's high press.
We saw how relentless Regis le Bris's side are. They overpowered the Gunners, and it was amazing to watch.
Many pundits talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been excellent, but Noah Sadiki, who plays alongside him, has also been one of the best acquisitions and should be recognised too.
I am expecting this being the best game|most exciting fixture